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. 2014 Jun 4;4:140. doi: 10.3389/fonc.2014.00140

Figure 2.

Figure 2

Common stresses and their effects on mitosis and Taxol response. A variety of stresses affect mitosis by acting directly or indirectly on the SAC. Stresses that maintain the SAC and/or increase microtubule stability often synergize (green line) with Taxol. In contrast, stresses that inhibit the MCC and/or disrupt microtubule formation commonly antagonize (red line) Taxol induced mitotic arrest and promote mitotic slippage.