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. Author manuscript; available in PMC: 2014 Jun 4.
Published in final edited form as: Brain. 2008 Jan 29;131(0 4):1123–1133. doi: 10.1093/brain/awn004

Figure 2.

Figure 2

MPO in EAE. (a) Western blotting confirmed the presence of MPO heavy chain in the brain specimen of mice induced with EAE. (b) Biochemical analysis of the MPO activity as a function of clinical staging demonstrated that higher clinical staging is associated with increased MPO activity. (c) There was increased demyelination at increasing clinilcal disease severity (R2=0.94, p=0.0021). (d) MPO activity of each animal vs. its clinical disease stage. A positive correlation was found with R2=0.73, p=0.014.