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. 2004 Apr 24;328(7446):983. doi: 10.1136/bmj.38050.593634.63

Table 6.

Relation between serum aminotransferase concentration and mortality from liver disease in men by follow up period. Figures are relative risks* (95% confidence intervals)

Year 1993-6 Year 1997-2000
Serum aspartate aminotransferase level (IU/I):

<20 1.0 (0.6 to 1.7) 1.0 (0.6 to 1.8)
20-29 1.8 (1.3 to 2.4) 3.3 (2.6 to 4.3)
30-39 6.4 (4.8 to 8.7) 10.0 (7.6 to 13.0)
40-49 17.2 (11.8 to 25.2) 36.3 (26.9 to 49.1)
50-99 46.8 (36.5 to 59.9) 89.4 (71.9 to 111.2)
≥100 61.6 (38.9 to 97.6) 178.8 (115.5 to 254.9)
Serum alanine aminotransferase level (IU/I):

<20 1.0 (0.6 to 1.6) 1.0 (0.7 to 1.5)
20-29 3.1 (2.4 to 4.2) 2.7 (2.1 to 3.4)
30-39 12.5 (9.7 to 16.3) 7.6 (5.8 to 9.9)
40-49 21.4 (15.2 to 30.2) 17.8 (13.1 to 24.2)
50-99 27.5 (20.4 to 36.9) 31.6 (25.0 to 40.0)
≥100 30.0 (16.0 to 55.9) 82.8 (58.4 to 117.5)
*

Adjusted for age, body mass index, smoking status, alcohol consumption, plasma glucose, serum total cholesterol, blood pressure, and family history of liver disease.