Table 1.
Characteristics | Total n=16,380 | HR+/HER2− n=10,247(62.6%) | Triple negative n=2,549 (15.6%) | HR+/HER2+ n=2,265 (13.8%) | HR−/HER2+ n=1,319 (8.1%) |
---|---|---|---|---|---|
n (%) | |||||
Nativity | |||||
US-Born | 7633 (46.6) | 4932 (48.1) | 1193 (46.8) | 976 (43.1) | 532 (40.3) |
Foreign-Born | 8747 (53.4) | 5315 (51.9) | 1356 (53.2) | 1289 (56.9) | 787 (59.7) |
Socioeconomic status | |||||
Quintile 1 (Low) | 4261 (26.0) | 2478 (24.2) | 713 (28.0) | 645 (28.5) | 425 (32.2) |
Quintile 2 | 3723 (22.7) | 2302 (22.5) | 608 (23.9) | 511 (22.6) | 302 (22.9) |
Quintile 3 | 3027 (18.5) | 1915 (18.7) | 485 (19.0) | 394 (17.4) | 233 (17.7) |
Quintile 4 | 2484 (15.2) | 1625 (15.9) | 348 (13.7) | 344 (15.2) | 167 (12.7) |
Quintile 5 (High) | 1683 (10.3) | 1170 (11.4) | 204 (8.0) | 207 (9.1) | 102 (7.7) |
Unknown/missing | 1433 (7.3) | 757 (7.4) | 191 (7.5) | 164 (7.2) | 90 (6.8) |
Hispanic enclave | |||||
Quintile 1 (Low) | 1359 (8.3) | 903 (8.8) | 197 (7.7) | 162 (7.2) | 97 (7.4) |
Quintile 2 | 2217 (13.5) | 1472 (14.4) | 333 (13.1) | 253 (11.2) | 159 (12.1) |
Quintile 3 | 2810 (17.2) | 1793 (17.5) | 440 (17.3) | 376 (16.6) | 201 (15.2) |
Quintile 4 | 3992 (24.4) | 2544 (24.8) | 605 (23.7) | 540 (23.8) | 303 (23.0) |
Quintile 5 (High) | 5261 (32.1) | 3062 (29.9) | 861 (33.8) | 837 (37.0) | 501 (38.0) |
Unknown/missing | 917 (4.5) | 473 (4.6) | 113 (4.4) | 97 (4.3) | 58 (4.4) |
Age at diagnosis (years) | |||||
<45 | 3633 (22.2) | 1867 (18.2) | 771 (30.2) | 641 (28.3) | 354 (26.8) |
45–49 | 2444 (14.9) | 1529 (14.9) | 373 (14.6) | 357 (15.8) | 185 (14.0) |
50–54 | 2348 (14.3) | 1380 (13.5) | 405 (15.9) | 336 (14.8) | 227 (17.2) |
55–59 | 2024 (12.4) | 1246 (12.2) | 308 (12.1) | 284 (12.5) | 186 (14.1) |
60–64 | 1720 (10.5) | 1179 (11.5) | 233 (9.1) | 197 (8.7) | 111 (8.4) |
≥65 | 4211 (25.7) | 3046 (29.7) | 459 (18.0) | 450 (19.9) | 256 (19.4) |
Marital status at diagnosis | |||||
Married | 9293 (56.7) | 5773 (56.3) | 1460 (57.3) | 1299 (57.4) | 761 (57.7) |
Never married | 2917 (17.8) | 1771 (17.3) | 463 (18.2) | 453 (20.0) | 230 (17.4) |
Previously married | 3598 (22.0) | 2351 (22.9) | 529 (20.8) | 453 (20.0) | 265 (20.1) |
Unknown | 793 (3.5) | 352 (3.4) | 97 (3.8) | 60 (2.6) | 63 (4.8) |
Insurance status† | |||||
Private/military | 8199 (50.1) | 5260 (51.3) | 1272 (49.9) | 1058 (46.7) | 609 (46.2) |
Public | 6825 (41.7) | 4161 (40.6) | 1062 (41.7) | 1020 (45.0) | 582 (44.1) |
Uninsured | 235 (1.4) | 142 (1.4) | 37 (1.5) | 36 (1.6) | 20 (1.5) |
Unknown | 1489 (6.8) | 684 (6.7) | 178 (7.0) | 151 (6.7) | 108 (8.2) |
Clinical Characteristics | |||||
AJCC tumor stage | |||||
I | 6034 (36.8) | 4379 (42.7) | 680 (26.7) | 667 (29.4) | 308 (23.4) |
II | 6186 (37.8) | 3644 (35.6) | 1170 (45.9) | 860 (38.0) | 512 (38.8) |
III | 2768 (16.9) | 1473 (14.4) | 472 (18.5) | 492 (21.7) | 331 (25.1) |
IV | 778 (4.7) | 409 (4.0) | 127 (5.0) | 141 (6.2) | 101 (7.7) |
Unknown | 1137 (3.7) | 342 (3.3) | 100 (3.9) | 105 (4.6) | 67 (5.1) |
Tumor grade | |||||
Low | 9053 (55.3) | 7321 (71.4) | 403(15.8) | 1054 (46.5) | 275 (20.8) |
High | 6659 (40.7) | 2501 (24.4) | 2065 (81.0) | 1115 (49.2) | 978 (74.1) |
Unknown | 1356 (4.1) | 425 (4.1) | 81 (3.2) | 96 (4.2) | 66 (5.0) |
Tumor size (cm) | |||||
0–2.00 | 8111 (49.5) | 5793 (56.5) | 910 (35.7) | 947 (41.8) | 461 (35.0) |
2.01–5.00 | 6065 (37.0) | 3370 (32.9) | 1188 (46.6) | 961 (42.4) | 546 (41.4) |
>5.00 | 1493 (9.1) | 743 (7.3) | 317 (12.4) | 227 (10.0) | 206 (15.6) |
Microinvasion | 132 (0.8) | 44 (0.4) | 32 (1.3) | 29 (1.3) | 27 (2.0) |
Diffuse | 85 (0.5) | 45 (0.4) | 11 (0.4) | 16 (0.7) | 13 (1.0) |
Unknown | 990 (3.0) | 252 (2.5) | 91 (3.6) | 85 (3.8) | 66 (5.0) |
Lymph node involvement | |||||
Negative | 9241 (56.4) | 6117 (59.7) | 1423 (55.8) | 1098 (48.5) | 603 (45.7) |
Positive | 6840 (41.8) | 3965 (38.7) | 1083 (42.5) | 1109 (49.0) | 683 (51.8) |
Unknown | 640 (1.8) | 165 (1.6) | 43 (1.7) | 58 (2.6) | 33 (2.5) |
Metastasis | |||||
Negative | 15255 (93.1) | 9644 (94.1) | 2368 (92.9) | 2055 (90.7) | 1188 (90.1) |
Positive | 778 (4.7) | 409 (4.0) | 127 (5.0) | 141 (6.2) | 101 (7.7) |
Unknown | 637 (2.1) | 194 (1.9) | 54 (2.1) | 69 (3.0) | 30 (2.3) |
Notes. Column percentages based on individuals with valid, non-missing information on risk factor.
Insurance status is based on payer source at diagnosis. Public insurance included Medicaid and other government-assisted programs; and private insurance included health maintenance organizations, preferred provider organizations, managed care not otherwise specified, and military care.