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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Am J Transplant. 2013 Dec 4;14(1):49–58. doi: 10.1111/ajt.12525

Figure 5. CD8 T cells do not reject MHC class I-deficient allogeneic BM via recognition of allogeneic MHC class II.

Figure 5

B10.S mice were given 3 Gy TBI on Day-1, anti-CD4 and anti-NK1.1 mAbs on Days −5, −1 and 5 and anti-CD8, 0.72 mg on each Days −5, −1 and 5 (when indicated in the table) prior to injection with 25×106 BM cells from the indicated donors. Donor chimerism in the MAC-1 and the B cell lineage 4 weeks after BMT is depicted. Each symbol represents an individual animal. Lines indicate mean values. *p<0.05 with a Kruskal-Wallis test followed by a Dunn’s multiple comparison test.