Fig. 1.

Covariance of skin and oral microbial community structure with disease subtype in immunodeficient patients. The variation in microbial diversity of 35 skin (a) and 21 oral samples (b) from healthy controls (green squares), and patients with CMC (red circles) and HIES (blue triangles). The principal coordinate plot uses the weighted UniFrac β-diversity metric, with the covariance of selected microbial taxa overlaid as a biplot. Organisms characteristic for the healthy skin samples are Staphylococcus and Corynebacterium spp., with Moraxellaceae spp. driving the different communities in disease.