Table 3. Activation of insulin signaling in gonadal WAT, muscle and liver of male and female mice.
pAkt/tAkt% of saline-injected groups was set at 100%, and pAkt/tAkt% of insulin-injected groups was calculated relative to saline-injected groups within the same sex and diet. pAkt/tAkt% of saline- and insulin-injected animals was listed at upper and lower rows respectively within each cell. An unpaired two-tailed t test was performed.
pAkt/tAkt (%) | Chow | SFA | MUFA | PUFA | ||
---|---|---|---|---|---|---|
WAT | Male | saline insulin |
100 ± 7.27 169.58 ± 25.88 ¶ P<0.05 |
100 ± 20.05 127.80 ± 35.36 |
100 ± 7.28 115.68 ± 46.13 |
100 ± 40.27 179.80 ± 29.81 |
Female | saline insulin |
100 ± 70.86 338.54 ± 20.13 ¶ P<0.0001 |
100 ± 34.73 413.25 ± 92.30 ¶ P<0.05 |
100 ± 3.06 205.20 ± 23.09 ¶ P<0.01 |
100 ± 13.28 184.47 ± 29.41 ¶ P<0.05 |
|
Muscle | Male | saline insulin |
100 ± 14.47 255.88 ± 5.23 ¶ P<0.0001 |
100 ± 58.79 139.10 ± 33.85 |
100 ± 28.22 127.86 ± 20.24 |
100 ± 28.63 140.31 ± 37.99 |
Female | saline insulin |
100 ± 40.68 310.11 ± 63.52 ¶ P<0.05 |
100 ± 45.47 215.73± 74.47 |
100 ± 38.21 202.06 ± 32.50 ¶ P<0.05 |
100 ± 21.10 212.31 ± 31.93 ¶ P<0.05 |
|
Liver | Male | saline insulin |
100 ± 5.96 231.60 ± 2.96 ¶ P<0.0001 |
100 ± 6.68 154.79 ± 23.95 |
100 ± 6.18 123.74 ± 18.05 |
100 ± 4.93 138.49 ± 24.75 |
Female | saline insulin |
100 ± 20.30 197.16 ± 30.33 ¶ P<0.05 |
100 ± 8.76 158.25 ± 19.33 ¶ P<0.05 |
100 ± 7.22 221.10 ± 26.38 ¶ P<0.01 |
100 ± 21.87 226.94 ± 39.76 ¶ P<0.05 |
Significantly different comparing to saline-treated group with the same sex and diet.