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. Author manuscript; available in PMC: 2014 Jun 4.
Published in final edited form as: Birth Defects Res A Clin Mol Teratol. 2010 Feb;88(2):111–127. doi: 10.1002/bdra.20631

Table 5. Cell cycle pathway.

A) Over and B) under expressed genes involved in the cell cycle pathway. Each column as described in Table 3.

Cell Cycle Pathway
Over-Expressed
1 2 3 4 5 6 7
Sequence ID Gene ID Description 0 CTL v 0 TCE 2 CTL v 2 TCE 8 CTL v 8 TCE 2 TCE v 0 TCE 2 TCE v 8 TCE 2 CTL v 0 CTL 2 CTL v 8 CTL
BC028526 Anapc13 anaphase promoting complex subunit 13
ENSMUST79362 Apc adenomatosis polyposis coli
ENSMUST37440 Atm ataxia telangiectasia mutated homolog (human)
ENSMUST86248 Aurkc aurora kinase C
ENSMUST74077 Bmp4 bone morphogenetic protein 4
NM_007561 Bmpr2 bone morphogenic protein receptor
ENSMUST107228 Brca1 breast cancer 1
ENSMUST44620 Brca2 breast cancer 2
ENSMUST93517 Casp3 caspase 3
NM_001081062 Ccno cyclin O
BC005775 Cdc26 cell division cycle 26
ENSMUST42410 Cdk6 cyclin-dependent kinase 6
ENSMUST22009 Cetn3 centrin 3
ENSMUST75853 Cks2 CDC28 protein kinase regulatory subunit 2
ENSMUST49404 Clasp1 CLIP associating protein 1
ENSMUST35089 Clasp2 CLIP associating protein 2
ENSMUST6293 Crkl v-crk sarcoma virus CT10 oncogene homolog (avian)-like
ENSMUST5841 Ctcf CCCTC-binding factor
ENSMUST31697 Cul1 cullin 1
ENSMUST26475 Ddit3 DNA-damage inducible transcript 3
AF396877 Dst dystonin
NM_013507 Eif4g2 eukaryotic translation initiation factor 4
ENSMUST81091 Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
BC048734 Fgf8 fibroblast growth factor 8
ENSMUST9777 G0s2 G0/G1 switch gene 2
ENSMUST43098 Gadd45a growth arrest and DNA-damage-inducible 45 alpha
ENSMUST32129 Gkn1 gastrokine 1
ENSMUST21729 Gpr132 G protein-coupled receptor 132
ENSMUST57884 Gps2 G protein pathway suppressor 2
ENSMUST23507 Gsk3b glycogen synthase kinase 3 beta
ENSMUST80030 Gspt1 G1 to S phase transition 1
ENSMUST38777 Hipk2 homeodomain interacting protein kinase 2
ENSMUST28882 Il1a interleukin 1 alpha
ENSMUST12587 Kif11 kinesin family member 11
U67204 Macf1 microtubule-actin crosslinking factor 1
ENSMUST4986 Mapk13 mitogen activated protein kinase 13
NM_134092 Mtbp Mdm2
ENSMUST52965 Nipbl Nipped-B homolog (Drosophila)
NM_010151 Nr2f1 nuclear receptor subfamily 2
ENSMUST78259 Nsl1 NSL1
ENSMUST25204 Pfdn1 prefoldin 1
ENSMUST18361 Pmp22 peripheral myelin protein
ENSMUST101534 Ptn pleiotrophin
ENSMUST49009 Rad9b RAD9 homolog B (S. cerevisiae)
ENSMUST28814 Rassf2 Ras association (RalGDS/AF-6) domain family 2
ENSMUST35842 Rassf4 Ras association (RalGDS/AF-6) domain family 4
ENSMUST22701 Rb1 retinoblastoma 1
ENSMUST29170 Rbl1 retinoblastoma-like 1 (p107)
ENSMUST34091 Rbl2 retinoblastoma-like 2
ENSMUST102864 Rel reticuloendotheliosis oncogene
NM_175238 Rif1 Rap 1 interacting factor 1 homolog (yeast)
ENSMUST73926 Rps12 ribosomal protein S12
ENSMUST27495 Sept2 septin 2
ENSMUST23095 Sept3 septin 3
ENSMUST30724 Sesn2 sestrin 2
ENSMUST57311 Sfn stratifin
BC086683 Spc24 SPC24
NM_001081008 Taf1 TAF1 RNA polymerase II
ENSMUST45288 Tgfb2 transforming growth factor
NM_172664 Tlk1 tousled-like kinase 1
AB020317 Trp53 transformation related protein 53
ENSMUST71648 Vegfa vascular endothelial growth factor A
Under-expressed
1 2 3 4 5 6 7
Sequence ID Gene ID Description 0 CTL v 0 TCE 2 CTL v 2 TCE 8 CTL v 8 TCE 2 TCE v 0 TCE 2 TCE v 8 TCE 2 CTL v 0 CTL 2 CTL v 8 CTL
BC028526 Anapc13 anaphase promoting complex subunit 13
ENSMUST25561 Anxa1 annexin A1
NM_009686 Apbb2 amyloid beta (A4) precursor protein-binding
ENSMUST29842 Bcl10 B-cell leukemia/lymphoma 10
AF271733 Bin3 bridging integrator 3
ENSMUST28836 Bmp2 bone morphogenetic protein 2
NM_007561 Bmpr2 bone morphogenic protein receptor
BC061001 Bmyc brain expressed myelocytomatosis oncogene
NM_009770 Btg3 B-cell translocation gene 3
NM_021550 C1galt1c1 C1GALT1-specific chaperone 1
BC052789 Cables2 Cdk5 and Abl enzyme substrate 2
ENSMUST93517 Casp3 caspase 3
ENSMUST48192 Ccdc5 coiled-coil domain containing 5
BC085238 Ccnb1 cyclin B1
BC060180 Ccng2 cyclin G2
ENSMUST114077 Ccnyl1 cyclin Y-like 1
BC005775 Cdc26 cell division cycle 26
ENSMUST50148 Cdc37l1 cell division cycle 37 homolog (S. cerevisiae)-like 1
BC003893 Cdc5l cell division cycle 5-like (S. pombe)
ENSMUST42410 Cdk6 cyclin-dependent kinase 6
ENSMUST23829 Cdkn1a cyclin-dependent kinase inhibitor 1A (P21)
ENSMUST3115 Cdkn1b cyclin-dependent kinase inhibitor 1B
BC049694 Cdkn3 cyclin-dependent kinase inhibitor 3
ENSMUST22009 Cetn3 centrin 3
ENSMUST68532 Cgrrf1 cell growth regulator with ring finger domain 1
ENSMUST29679 Cks1b CDC28 protein kinase 1b
ENSMUST75853 Cks2 CDC28 protein kinase regulatory subunit 2
ENSMUST27050 Cops5 COP9 (constitutive photomorphogenic) homolog
ENSMUST17920 Crk v-crk sarcoma virus CT10 oncogene homolog (avian)
ENSMUST4478 Cul3 cullin 3
NM_027545 Cwf19l2 CWF19-like 2
ENSMUST103129 Dsn1 DSN1
ENSMUST103145 E2f1 E2F transcription factor 1
AY957576 E2f8 E2F transcription factor 8
ENSMUST1757 Eef1e1 eukaryotic translation elongation factor 1 epsilon 1
NM_001003817 Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2
ENSMUST81091 Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
NM_007951 Erh enhancer of rudimentary homolog (Drosophila)
NM_011809 Ets2 E26 avian leukemia oncogene 2
ENSMUST81028 Etv6 ets variant gene 6 (TEL oncogene)
NM_001033244 Fancd2 Fanconi anemia
ENSMUST19907 Fbxo5 F-box protein 5
ENSMUST187 Fgf6 fibroblast growth factor 6
ENSMUST62292 Foxc1 forkhead box C1
ENSMUST15456 Gadd45b growth arrest and DNA-damage-inducible 45 beta
ENSMUST32129 Gkn1 gastrokine 1
NM_008179 Gspt2 G1 to S phase transition 2
ENSMUST34026 Hpgd hydroxyprostaglandin dehydrogenase 15 (NAD)
BC024581 Hrasls3 HRAS like suppressor 3
ENSMUST65537 Jmy junction-mediating and regulatory protein
ENSMUST103032 Llgl2 lethal giant larvae homolog 2 (Drosophila)
NM_010755 Maff v-maf musculoaponeurotic fibrosarcoma oncogene family
ENSMUST25078 Map3k8 mitogen activated protein kinase kinase kinase 8
ENSMUST88827 Mapk12 mitogen-activated protein kinase 12
ENSMUST57669 Mapk3 mitogen activated protein kinase 3
NM_133350 Mapre3 microtubule-associated protein
ENSMUST34303 Mphosph6 M phase phosphoprotein 6
NM_134092 Mtbp Mdm2
ENSMUST22971 Myc myelocytomatosis oncogene
NM_144931 Nae1 NEDD8 activating enzyme E1 subunit 1
NM_133762 Ncapg2 non-SMC condensin II complex
ENSMUST35800 Nfatc1 nuclear factor of activated T-cells
NM_010151 Nr2f1 nuclear receptor subfamily 2
NM_001024622 Pcnp PEST proteolytic signal containing nuclear protein
ENSMUST25204 Pfdn1 prefoldin 1
ENSMUST36374 Phb prohibitin
ENSMUST34689 Pin1 protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
ENSMUST56370 Pmf1 polyamine-modulated factor 1
NM_198600 Pols polymerase (DNA directed) sigma
NM_008014 Ppm1g protein phosphatase 1G (formerly 2C)
NM_024209 Ppp6c protein phosphatase 6
ENSMUST20685 Pttg1 pituitary tumor-transforming 1
ENSMUST22136 Rad17 RAD17 homolog (S. pombe)
ENSMUST20649 Rad50 RAD50 homolog (S. cerevisiae)
ENSMUST90678 Rap1a RAS-related protein-1a
ENSMUST22701 Rb1 retinoblastoma 1
ENSMUST27040 Rb1cc1 RB1-inducible coiled-coil 1
ENSMUST102598 Rbbp4 retinoblastoma binding protein 4
ENSMUST34091 Rbl2 retinoblastoma-like 2
BC051473 Rbx1 ring-box 1
ENSMUST84250 Rcc1 regulator of chromosome condensation 1
NM_007483 Rhob ras homolog gene family
NM_028228 Rik RIKEN cDNA 2610028A01 gene
ENSMUST73926 Rps12 ribosomal protein S12
NM_009101 Rras Harvey rat sarcoma oncogene
BC010774 S100a6 S100 calcium binding protein A6 (calcyclin)
ENSMUST23457 Senp5 SUMO/sentrin specific peptidase 5
ENSMUST30724 Sesn2 sestrin 2
BC086683 Spc24 SPC24
NM_001005370 Spin2 spindlin family
ENSMUST29448 Sycp1 synaptonemal complex protein 1
ENSMUST11258 Tbrg1 transforming growth factor beta regulated gene 1
ENSMUST2678 Tgfb1 transforming growth factor
ENSMUST39562 Trim13 tripartite motif protein 13
NM_021884 Tsg101 tumor susceptibility gene 101
ENSMUST25914 Vegfb vascular endothelial growth factor B
ENSMUST21985 Zfp369 zinc finger protein 369