Table I. Treatment outcome after oxaliplatin given 24 h before fever-range whole body thermal therapy.
Group, Outcome | Number (% of treated) |
Maximum relative tumor volume (average for group) |
Median Survival (days [range]) |
Mean Survival (days) |
---|---|---|---|---|
Untreated controls | 35 | 91.6 | 23 [19–30] | 24 |
Treated, non-responders (NR) | 8 (22%) | 51.4§ | 26 [21–30] | 27 |
Treated, limited responders (LR) |
6 (17%) | 15.2§§ | 35 [25–41] | 33§ |
Treated, complete responders (CR) |
4 (11%) | 17.3§§ | 44 [26–84] | 50§ |
Treated, cures | 18 (50%) | 8.5§§ | 588 [224–729]* | 588§§,^ |
p<0.05,
p<0.00001 compared to controls,
7 rats are still alive