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. 2014 May 27;2:e392. doi: 10.7717/peerj.392

Table 3. QTL results for the body composition traits measured in the F11 mice.

Shown are all QTLs affecting the body composition traits measured in the F11 mice that had LOD scores reaching the 10% (suggestive) or 5% () experimentwise level of significance. Locations on each chromosome (Ch) and confidence intervals of the QTLs are given in Mb (from NCBI Build 37). Also shown is the percentage contribution (%) of each QTL to the total variance of each trait, and its additive (a), dominance (d) genotypic effects (bolded values indicate significance at P < 0.05). Interactions of QTLs with sex are indicated as M (significant in males only), F (significant in females only) or both M and F (significant in both sexes where bolded values indicate the sex for which the QTL had the greater effect).

Trait Ch Location Conf. Interval LOD a d % Sex
FAT 2 19.7 11.6–26.2 5.45 0.2148 0.0548 2.49 F
3 99.8 83.1–114.7 4.64 −0.1248 0.2227 2.83
6 124.0 118.8–126.4 5.44 0.1691 −0.0325 1.75
10 75.3 65.0–91.5 4.18 −0.1435 −0.0349 1.24
17 48.6 34.9–57.1 4.49 0.2135 0.0262 2.45
X 54.2 48.3–58.1 5.45 −0.1337 0.0583 1.49
PFAT 1 25.5 21.4–35.8 3.75 −0.3262 0.0436 1.13
2 21.0 12.8–29.4 3.98 0.4411 0.1667 1.93
3 95.6 80.6–102.1 8.98 −0.5424 0.5023 5.22
6 124.0 117.4–126.6 4.50 0.3774 −0.0858 1.61
10 72.7 67.4–92.7 4.42 −0.4117 −0.0143 1.76
X 107.7 101.5–126.4 4.45 0.3491 −0.1171 1.35
SUBQ 2 19.4 12.7–29.0 7.42 0.0120 0.0017 4.78
3 81.6 79.7–106.9 4.40 −0.0062 0.0030 1.72
6 124.0 119.0–126.6 4.27 0.0070 −0.0019 1.91
10 92.0 82.7–100.0 4.56 −0.0091 −0.0091 4.32
17 48.6 34.9–62.7 3.77 0.0093 0.0014 2.88
PSUBQ 2 19.4 11.5–29.4 5.92 0.0314 0.0067 3.56
3 81.6 79.7–100.9 6.57 −0.0229 0.0091 2.39
10 92.0 84.0–98.2 4.76 −0.0270 −0.0271 4.17
10 127.2 114.0–130.3 3.81 −0.0227 −0.0035 2.16
GON 6 124.0 118.0–126.3 6.48 0.0175 −0.0011 2.02 M
X 58.4 54.1–66.5 4.01 −0.0265 −0.0002 1.06 M
PGON 3 95.6 79.5–104.5 4.46 −0.0280 0.0627 3.01
6 124.0 117.4–126.3 6.11 0.0477 0.0090 2.18 M, F
X 109.9 101.5–126.4 6.38 0.0467 −0.0147 2.10
BAT 6 125.7 122.6–128.9 4.13 0.0024 0.0001 1.77
PBAT X 107.7 104.1–125.8 3.85 0.0056 0.0010 1.52
LIVER 2 74.1 69.2–78.9 4.40 0.0443 −0.0045 1.32 F
2 104.5 98.0–106.7 4.05 0.0344 0.0222 0.95
2 140.1 135.9–146.2 4.47 0.0458 −0.0077 1.74
7 122.7 114.4–129.8 4.88 −0.0689 −0.0335 3.14
8 83.6 81.6–85.8 3.80 0.0390 −0.0110 1.06
17 44.2 31.6–49.8 3.85 0.0410 0.0080 1.11
PLIV 1 96.7 89.4–117.1 3.82 0.0663 0.1151 2.79
6 99.5 91.7–112.4 4.58 −0.1243 −0.0939 3.33
11 102.1 98.8–107.8 4.55 −0.0889 −0.0333 2.46
19 7.5 5.3–10.2 4.01 0.0760 −0.0205 1.53 M, F
X 107.7 108.6–125.8 6.70 0.0963 0.0292 2.79
HEART 3 77.1 70.0–77.1 4.08 0.0041 0.0056 0.99
8 127.6 126.4–130.1 4.09 0.0065 −0.0009 1.67
SPLEEN 1 127.2 124.4–133.5 4.11 0.0047 −0.0026 1.76
8 74.8 51.2–80.8 6.91 0.0072 0.0002 2.88
12 81.9 78.3–82.9 19.26 0.0098 −0.0087 7.82
17 38.0 31.8–49.4 10.47 0.0085 −0.0017 4.79
PSPLEEN 1 127.2 123.3–131.6 4.57 0.0149 −0.0056 1.63
8 67.4 58.5–82.5 5.40 0.0170 −0.0018 1.74 M, F
12 81.9 80.8–84.7 16.23 0.0234 −0.0254 5.03
17 38.0 31.8–49.4 8.49 0.0207 −0.0046 2.84 M, F
19 4.0 4.0–6.5 3.81 0.0090 −0.0114 1.10 M, F
X 124.7 106.8–126.4 9.50 0.0185 0.0169 3.46 M, F
X 136.6 133.1–137.8 9.41 0.0167 0.0177 3.11 M, F