Table 4.
PET response data
| Dose level mg/kg | Diagnosis | Baseline max SUV | Cycle 1 Max SUV (% change from baseline) | Cycle 3 Max SUV (% change from baseline) | Number of cycles on study |
|---|---|---|---|---|---|
| 1.5 | Retroperitoneal sarcoma | 15.90 | 10.50 (−33.96) | 9.9 (−37.74) | 8 |
| 5.0 | Synovial sarcoma | 1.85 | 1.25 (−34.83) | 1.40 (−26.67) | 7 |
| 20.0 | Rhabdomyosarcoma | 6.15 | 4.80 (−22.12) | 4.25 (−31.71) | 4 |
| 20.0 | Adrenal cortical Ca | 12.7 | 9 (−29.13) | 12.3 (−0.03) | 10 |
| 30.0 | Spindle cell sarcoma | 7.50 | 4.70 (−38.74) | 4.25 (−44.71) | 5 |
| 30.0 | Ewing’s sarcoma | 6.55 | 3.30 (−50.47) | 4.13 (−37.96) | 3 |
| 30.0 | Adenosarcoma of uterus | 5.30 | 3.05 (−42.69) | 4.70 (−11.13) | 4 |
| 30.0 | High grade spindle cell sarcoma NOS | 3.55 | ND | 2.15 (−39.74) | 7 |