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Myofibroblasts in the heart. As myofibroblasts represent a contractile phenotype of the fibroblasts, staining with α-smooth muscle actin (dark brown color) reveals the location of several myofibroblasts (indicated by the arrows) in the mouse heart. Small in size, these cells reside in close proximity to neighboring cardiac myocytes and are clearly distinguishable from vascular smooth muscle cells localized around blood vessels (BV). Scale bar = 25 µm.
