Western blot results for serum samples obtained from experimentally vaccinated dogs prior to and at various times (weeks) following initial vaccination. Vaccine was administered to dogs at weeks 0, 2, 33, 36, and 39; WB results are shown for sera collected at weeks 0, 5, 33, 34, and 40. Serum samples were obtained prior to vaccination at weeks 0 and 33. (A) Fort Dodge LymeVax vaccine, administered to dogs FD1, FD2, and FD3; (B) Schering-Plough Galaxy Lyme vaccine, administered to dogs SP1, SP2, and SP3; (C) Merial RECOMBITEK Lyme vaccine, administered to dogs M1, M2, and M3; (D) positive control. Sera from the unvaccinated control dog failed to produce clearly visible bands in the WB assay at any time. WBs were run with the QualiCode canine Lyme disease kit (Immunetics, Inc.) as described in Materials and Methods.