TABLE 1.
Vaccine | Sample time | SNAP 3Dx result | IFA titer, dog 1, 2, 3 | WB result, (molecular mass[es] of reactive band[s] [kDa]) | C6 peptide microtiter plate ELISA result (mean ODb) |
---|---|---|---|---|---|
LymeVax (Fort Dodge-Animal Health) | Prebleed | Neg | All < 100 | Neg | 0.053 |
Wk 5 | Neg | 1,600, 1,600, 800 | 41, 34, 31, 18 | 0.060 | |
Wk 33 | Neg | 400, 400, 100 | 41, 39, 34, 31, 21, 18 | 0.061 | |
Wk 34 | Neg | 1,600, 1,600, 1,600 | 93, 66, 60, 58, 41, 39, 34, 31, 21, 18 | 0.062 | |
Wk 40 | Neg | 6,400, 1,600, 1,600 | 93, 66, 60, 58, 41, 39, 34, 31, 30, 28, 23, 21, 18 | 0.073 | |
Wk 43 | Neg | 3,200, 1,600, 1,600 | Not tested | 0.069 | |
Galaxy (Schering-Plough Animal Health) | Prebleed | Neg | All < 100 | Neg | 0.043 |
Wk 5 | Neg | 1,600, 1,600, 1,600 | 66, 58, 41, 39, 34, 31, 21, 18 | 0.079 | |
Wk 33 | Neg | 400, 100, 100 | 66, 58, 39, 34, 31, 21 | 0.072 | |
Wk 34 | Neg | 3,200, 1,600, 1,600 | 93, 66, 60, 58, 41, 39, 34, 31, 30, 23, 21, 18 | 0.069 | |
Wk 40 | Neg | 6,400, 6,400, 3,200 | 93, 66, 60, 58, 41, 39, 34, 31, 30, 23, 21, 18 | 0.078 | |
Wk 43 | Neg | 3,200, 3,200, 3,200 | Not tested | 0.072 | |
RECOMBITEK Lyme (Merial) | Prebleed | Neg | All < 100 | 41 | 0.043 |
Wk 5 | Neg | 800, 800, 800 | 41, 31 | 0.087 | |
Wk 33 | Neg | 100, 100, 100 | 41, 31 | 0.058 | |
Wk 34 | Neg | 1,600, 1,600, 800 | 93, 66, 41, 31, 18 | 0.060 | |
Wk 40 | Neg | 3,200, 3,200, 3,200 | 93, 66, 41, 31, 18 | 0.064 | |
Wk 43 | Neg | 1,600, 1,600, 800 | Not tested | 0.065 | |
None (control) | Prebleed | Neg | All < 100 | Neg | 0.055 |
Wk 5 | Neg | All < 100 | Neg | 0.054 | |
Wk 33 | Neg | All < 100 | Neg | 0.066 | |
Wk 34 | Neg | All < 100 | Neg | 0.055 | |
Wk 40 | Neg | All < 100 | Neg | 0.053 | |
Wk 43 | Neg | All < 100 | Not tested | 0.067 |
Neg, negative.
OD, optical density at 650 nm. Assay cutoff, 0.097.