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Murine GM-CSF levels in serum in GM-C79 transgenic and nontransgenic littermate mice after intraperitoneal administration of 25 μg of LPS (transgenic animals, 9 males and 4 females; nontransgenic animals, 10 males and 9 females). Blood was taken from the tail vein just prior to LPS administration and at 6, 12, 24, and 48 h afterward for quantification of murine GM-CSF by ELISA. Pooled data from two independent experiments are shown.
