Table 4.

Variables according to polymorphism in Nrf2 gene.

		rs35652124				rs6721961
		GG+GA	AA	p value1	p value 2	CC+CA	AA	p value1	p value 2
Total
n		175	41			197	19
Diastolic BP	(mmHg)	74.2±13.1	79.9±14.2	0.024	0.047
Albumin	(g/l)	41.0±3.5	42.4±3.9	0.018	ns
Homocysteine	(μmol/l)					37.62±23.61	30.03±7.14	0.002	ns
Troponin T	(μg/l)	0.035±0.060	0.016±0.032	0.006	ns	0.033±0.058	0.014±0.018	0.001	ns
Male
n		99	20			108	11
HD-duration	(year)					9.25±8.73	3.83±3.56	0.001	-
Homocysteine	(μmol/l)					39.89±23.67	28.94±6.73	0.001	ns
β2-microglobulin	(mg/l)	33.3±7.6	27.9±7.8	0.007	0.034
CACS	(mm3)	1605±2165	579±1186	0.003	ns	1533±2130	444±630	<0.001	ns
Troponin T	(μg/l)	0.042±0.070	0.019±0.036	0.030	ns	0.041±0.069	0.013±0.019	0.002	ns
Female
n		76	21			89	8
Systolic BP	(mmHg)	132.6±26.9	150.3±26.9	0.012	0.002	133.6±23.3	163.1±32.6	0.003	0.001
Diastolic BP	(mmHg)	70.1±11.8	85.1±13.4	<0.001	<0.001	72.3±13.1	82.9±15.3	0.048	0.039
Platelet	(×103/μl)					185±56	146±14	<0.001	ns
Albumin	(g/l)	40.1±3.5	42.1±3.5	0.020	0.013

¹ Unadjusted analysis (Student's t-test or Welch's t-test)

² Multivariate analysis adjusted for age, HD-duration, diabetes (yes or no) and Kt/V

ns: not significant