FIG. 3.

Ability of PBMC to respond to low concentrations of E6 protein. Open bars show the percentage of controls (n = 8) responding to ≤3.12 ng of recombinant E6/ml for IFN-γ, IL-12, IL-18, and IL-10. Gray bars show the percentage of mild-to-moderate patients with RRP (n = 3) responding, and black bars show the percentage of patients with severe disease (n = 9) responding. Comparisons between controls, and each group of patients were performed by using a two-sided Fisher exact test with Bonferroni correction.