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(A) Immunoreactivity to 4-hydroxi-2-neonenal (4-HNE, red) in the retina and RPE/choroid of mice expressing different levels of GPx4. Nuclei was counterstained with 4,6-diamidino-2-phenylindole (DAPI, blue). Scale bar, 30 µm. (B) Statistical evaluation of the immunofluorescence for 4-HNE in RPE/choroid (mean±SEM, n = 4).
