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. 2014 Jun 4;9(6):e98718. doi: 10.1371/journal.pone.0098718

Figure 1. Genetic mutations in pure pancreatic juice.

Figure 1

The y-axis of the figure represents the percentage of cases with mutations in each gene. A. No mutation was detected in the pure pancreatic juice from cases with normal pancreas tissue. B. GNAS mutation was detected in one case (4.5%) with CP (chronic pancreatitis) and a small cystic lesion. C. GNAS and KRAS mutations were detected in 7.7% (three of 39 cases) and 20.5% (eight of 39 cases), respectively, that had pancreatic ductal adenocarcinoma (PDAC). The GNAS mutation was detected in all cases with intraductal papillary mucinous neoplasm (IPMN, n = 3). D. GNAS and KRAS mutations were detected in 41.5% (34 of 82 cases) and 39.0% (32 of 82 cases), respectively, with IPMN.