Table 4. Cancer-related gene profiling in resected pancreatic tumours.

Case	Age	Sex		Diagnosis		GNAS			KRAS
					Mutation	VF (%)	Coverage	Mutation	VF (%)	Coverage
1	62	M			WT			G12D	23.0	634
2	73	M			WT			G12R	16.4	691
3	68	M			WT			G12D	12.2	809
4	63	F			WT			G12V	6.9	800
5	62	F			WT			G12V	8.8	2567
6	77	M			WT			G12D	11.8	1441
7	51	F			WT			G12D	12.0	1731
8	72	M			WT			G12D	14.5	689
9	77	F			WT			G12V	20.3	723
10	65	F			WT			G12D	20.5	985
11	67	M			WT			G12V	34.8	863
12	60	M			WT			A146T	1.21	990	†
13	53	M		without IPMN	WT			G12D	19.24	2355	†
14	67	M			WT			G12D	16.13	595	†
15	78	M			WT			G12D	1.87	268	†
6	73	F			WT			G12R	28.22	1244	†
17	57	F			WT			G12R	55.63	6899	†
18	52	M			WT			G12V	13.59	2126	†
19	72	F			WT			G12V	4.92	488	†
20	71	F			WT			G12V	32.44	4263	†
21	61	M	PDAC		WT			G12V	30.55	4458	†
22	78	M			WT			Q61H	23.27	1985	†
23	78	F			WT			WT			†
24	80	F			WT			WT			†
25	71	F			WT			WT
26	67	M			WT			WT
27	82	F			R201C	5.5	2321	G12D	6.5	1364
28	78	M			R201H	13.8	4075	G12D	13.2	2058	†
29	72	M			R201H	5.7	2440	G12D	14.4	2145
30	69	M		with IPMN	R201C	1.0	2235	WT			†
31	80	M		(PDAC concomitant	R201H	5.8	925	WT
32	73	M		with IPMN)	WT			G12V	25.4	688	†
33	78	F			WT			G12V	6.5	851	†
34	73	M			WT			G12V	1.9	1134	†
35	63	F			WT			G12D	11.3	1185
36	79	F			WT			G12D	14.9	2563	†
37	72	M			R201C	10.4	501	G12V	10.5	467
38	79	M			R201C	11.8	2154	G12D	16.2	1292	†
39	79	F		PDAC derived from	WT			Q61H	10.5	873
40	80	F		IPMN	WT			G12D	16.9	2330	†
41	69	M			WT			WT
42	37	M			WT			WT
43	81	M			R201H	46.6	1302	Q61H	48.0	1628
44	69	M			R201C	49.6	1215	G12D	42.9	815
45	78	F	IPMN	without PDAC	WT			G12V	39.3	751
46	62	M			R201H	39.4	1089	G12V	38.3	650
47	67	M			R201H	16.1	1051	G12D	16.2	1183
48	76	M			WT			G12D	7.0	512

VF, Variant frequency; WT, wild type;

PDAC, pancreatic ductal adenocarcinoma; IPMN, intraductal papillary mucinous neoplasm.

^†DNA from formalin-fixed, paraffin-embedded samples.