Table 5. Comparison of detected mutations between the pancreatic juice and resected tissue.

						GNAS		KRAS
Case	Age	Sex	Diagnosis	IPMN-Type		Mutation	VF (%)	Mutation	VF (%)
1	73	M				WT		G12R	16.35
						WT		WT
2	62	F				WT		G12V	8.77
			PDAC without			WT		WT
3	68	M	IPMN			WT		G12D	12.24
						WT		WT
4	62	M				WT		WT
						WT		G12D	23.03
5	82	F		Branch		R201C	5.47	G12D	6.45
						R201C	12.77	WT
6	73	M		Branch		WT		G12V	1.94
						WT		G12V	31.79
7	78	F		Branch		WT		G12V	6.46
						WT		G12V	12.79
8	72	M	PDAC	Branch		R201H	5.7	G12D	14.36
			concomitant			WT		WT
9	63	F	with IPMN	Branch		WT		G12D	11.31
						WT		WT
10	73	M		Branch		WT		G12V	25.44
						WT		WT
11	80	F		Branch		WT		G12D	16.91
						WT		WT
12	80	M		Branch		R201H	5.84	WT
						WT		WT
13	72	M		Main duct		R201C	10.38	G12V	10.49
						R201C	27.82	G12V	21.62
14	69	M	PDAC derived	Main duct		WT		WT
			from IPMN			R201C	8.9	G12V	17.17
15	37	M		Branch		WT		WT
						WT		WT
16	67	M		Main duct		R201H	10.53	G12D	16.2
						R201H	16.08	G12D	16.23
17	81	M		Main duct		R201H	46.62	Q61H	48.03
						R201H	14.39	Q61H	17.46
18	76	M		Main duct		WT		G12D	7.03
			IPMN			WT		G12D	17.28
19	78	F	(Noninvasive)	Main duct		WT		G12V	39.28
						WT		G12V	25.22
20	79	F		Main duct		WT		Q61H	10.54
						WT		WT
21	62	M		Branch		R201H	39.39	G12V	38.31
						R201H	9.38	G12D	5.92
No. of detected mutations in tissue samples						7		17
No. of pancreatic juice mutations identical to tissue samples						5		7
Concordance rate of mutation					(%)	71.4		41.2

Upper lines of each case indicate the results for tissue samples and lower lines indicate the results for pancreatic juice.

VF, Variant frequency; WT, wild type;

PDAC, pancreatic ductal adenocarcinoma; IPMN, intraductal papillary mucinous neoplasm.