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. 2014 Jun 4;9(6):e98989. doi: 10.1371/journal.pone.0098989

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Plasma sCD14 levels, like the other markers of immune activation, were elevated in HIV-1 viremic patients compared to healthy controls (Panel A). Levels of sCD14 and plasma IL-27 levels were plotted (Panel B) but no correlation was observed. Plasma sCD163 levels were elevated in HIV-1 viremic patients compared to healthy controls (Panel C), with a trend towards higher levels of sCD14 with higher HIV-1 viral loads. Levels of sCD163 and plasma IL-27 levels were plotted (Panel B) and, unlike the other markers measured, there was a significant Spearman r noted (Spearman r = 0.12, p = 0.005) (Panel D).