Table 3. Multiple regression analysis of lower- or higher-intensity LTPA with metabolic and inflammatory variables.

		Lower-intensity LTPA (MET h/w)		Higher-intensity LTPA (MET h/w)
		Regression coefficient	p value	Regression coefficient	p value
		(per 1 MET h/w increase)		(per 1 MET h/w increase)
BMI (kg/m2)	Model 1	−0.0194	<0.001	−0.0176	<0.001
	Model 2+higher (lower)-intensity LTPA	−0.0195	<0.001	−0.0164	<0.001
Waist circumference (cm)	Model 1	−0.0461	<0.001	−0.0748	<0.001
	Model 2+higher (lower)-intensity LTPA	−0.0449	<0.001	−0.0679	<0.001
	+BMI	−0.0013	ns	−0.0313	<0.001
HbA1c (%) (mmol/mol)	Model 1	−0.0003 (−0.0033)	ns	−0.0005 (−0.0055)	<0.001
	Model 2+higher (lower)-intensity LTPA	−0.0002 (−0.0022)	ns	−0.0003 (−0.0033)	0.003
	+BMI	−0.0001 (−0.0011)	ns	−0.0003 (−0.0033)	0.027
HOMA2-IR	Model 1	−0.0016	0.069	−0.0038	<0.001
	Model 2+higher (lower)-intensity LTPA	−0.0015	0.092	−0.0034	<0.001
	+BMI	−0.0006	ns	−0.0026	<0.001
Triglyceride (mmol/l)	Model 1	−0.0024	<0.001	−0.0030	<0.001
	Model 2+higher (lower)-intensity LTPA	−0.0022	0.001	−0.0027	<0.001
	+BMI	−0.0015	0.016	−0.0021	<0.001
HDL-cholesterol (mmol/l)	Model 1	0.0020	<0.001	0.0027	<0.001
	Model 2+higher (lower)-intensity LTPA	0.0019	<0.001	0.0024	<0.001
	+BMI	0.0014	0.003	0.0020	<0.001
HS-CRP (mg/l)	Model 1	−0.0053	0.002	−0.0062	<0.001
	Model 2+higher (lower)-intensity LTPA	−0.0051	0.003	−0.0054	<0.001
	+BMI	−0.0032	0.054	−0.0039	0.002

Lower- and higher-intensity was defined as <3.6 METs (mean of study participants) and ≥3.6 METs, respectively.

Abbreviations: LTPA, leisure-time physical activity; METs, metabolic equivalents; BMI, body mass index; HbA_1c, hemoglobin A_1c; HOMA2-IR, homeostasis model assessment 2 of insulin resistance; HDL, high density lipoprotein; HS-CRP, high sensitivity C-reactive protein.

Model 1, adjusted for age and sex; Model 2, adjusted for age, sex, duration of diabetes, current smoking, current drinking, energy intake, cardiovascular diseases, depressive symptoms and treatment of diabetes.