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Representative scotopic (A) and photopic (C) electroretinograms from WT and SIRT6-KO mice at different light intensities (dBs). Plots B and D depict average amplitudes of a-wave and b-wave. Note that the fold decrease of the scotopic a-wave amplitude (8) is greater than the fold decrease of the photopic a-wave amplitude (2,5). Data are mean ± SE (n = 4). **p<0.01, ***p<0.001.
