Table 3.
Sarcosine metabolism phenotypes of different breast cancer subtypes
| Parameter | Total (N =721) (%) | Luminal A (n =303) (%) | Luminal B (n =169) (%) | HER-2 (n =71) (%) | TNBC (n =178) (%) | P -value |
|---|---|---|---|---|---|---|
|
Sarcosine metabolic type |
|
|
|
|
|
0.003 |
| High sarcosine type |
36 (5.0) |
16 (5.3) |
12 (7.1) |
7 (9.9) |
1 (0.6) |
|
| Intermediate sarcosine type |
21 (2.9) |
14 (4.6) |
4 (2.4) |
1 (1.4) |
2 (1.1) |
|
| Low sarcosine type |
219 (30.4) |
93 (30.7) |
54 (32.0) |
26 (36.6) |
46 (25.8) |
|
| Null type | 445 (61.7) | 180 (59.4) | 99 (58.6) | 37 (52.1) | 129 (72.5) |
Bold number represents p<0.05.
TNBC, triple negative breast cancer.