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. 2014 Jun 4;9(6):e99164. doi: 10.1371/journal.pone.0099164

Table 3. Association between MRI-DRAGON parameters and poor outcome at 3 month (n = 230).

mRS >2 mRS ≤2 Univariate analysis Multivariate analysis
N = 78 N = 152
n (%) n (%) OR (95% CI) p-value Adjusted OR (95% CI) p-value
MRI-DRAGON parameters
M1 occlusion
Yes 43 (55) 32 (21) 4.61 (2.55–8.33) <0.0001 1.58 (0.71–3.52) 0.26
No 35 (45) 120 (79) 1.00
DWI-ASPECTS
≤5 19 (24) 14 (9) 3.17 (1.49–6.75) 0.003 1.14 (0.42–3.12) 0.80
>5 59 (76) 138 (91) 1.00
Prestroke mRS>1
Yes 13 (17) 10 (7) 2.84 (1.18–6.81) 0.02 1.93 (0.63–5.92) 0.25
No 65 (83) 142 (93) 1.00
Age
≥80 years 42 (54) 39 (26) 4.16 (2.04–8.52) 0.0001 3.01 (1.25–7.29) 0.02
65–79 years 21 (27) 55 (36) 1.48 (0.69–3.15) 1.23 (0.49–3.07)
<65 years 15 (19) 58 (38) 1.00 1.00
Glucose level
>8 mmol/L 25 (32) 28 (18) 2.09 (1.12–3.91) 0.02 1.83 (0.84–3.97) 0.13
≤8 mmol/L 53 (68) 124 (82) 1.00
Onset-to-treatment time
>90 min 73 (94) 140 (92) 1.25 (0.43–3.69) 0.68 1.45 (0.39–5.46) 0.58
≤90 min 5 (6) 12 (8) 1.00
NIHSS score on admission 1.22 (1.15–1.30)* <0.0001* 1.19 (1.11–1.28)* <0.0001*
>15 36 (46) 11 (7) - -
10–15 20 (26) 32 (21) - -
5–9 13 (17) 61 (40) - -
0–4 9 (11) 48 (32) - -

All variables included in the multivariate model are presented in the table. M1  =  M1 segment of the middle cerebral artery. * per 1-point NIHSS score increase.

mRS: Modified Rankin scale. NIHSS: National Institute of Health Stroke Scale. DWI-ASPECTS: Diffusion-weighted imaging Alberta Stroke Programme Early CT score.