Table 3. Association between MRI-DRAGON parameters and poor outcome at 3 month (n = 230).
mRS >2 | mRS ≤2 | Univariate analysis Multivariate analysis | ||||
N = 78 | N = 152 | |||||
n (%) | n (%) | OR (95% CI) | p-value | Adjusted OR (95% CI) | p-value | |
MRI-DRAGON parameters | ||||||
M1 occlusion | ||||||
Yes | 43 (55) | 32 (21) | 4.61 (2.55–8.33) | <0.0001 | 1.58 (0.71–3.52) | 0.26 |
No | 35 (45) | 120 (79) | 1.00 | |||
DWI-ASPECTS | ||||||
≤5 | 19 (24) | 14 (9) | 3.17 (1.49–6.75) | 0.003 | 1.14 (0.42–3.12) | 0.80 |
>5 | 59 (76) | 138 (91) | 1.00 | |||
Prestroke mRS>1 | ||||||
Yes | 13 (17) | 10 (7) | 2.84 (1.18–6.81) | 0.02 | 1.93 (0.63–5.92) | 0.25 |
No | 65 (83) | 142 (93) | 1.00 | |||
Age | ||||||
≥80 years | 42 (54) | 39 (26) | 4.16 (2.04–8.52) | 0.0001 | 3.01 (1.25–7.29) | 0.02 |
65–79 years | 21 (27) | 55 (36) | 1.48 (0.69–3.15) | 1.23 (0.49–3.07) | ||
<65 years | 15 (19) | 58 (38) | 1.00 | 1.00 | ||
Glucose level | ||||||
>8 mmol/L | 25 (32) | 28 (18) | 2.09 (1.12–3.91) | 0.02 | 1.83 (0.84–3.97) | 0.13 |
≤8 mmol/L | 53 (68) | 124 (82) | 1.00 | |||
Onset-to-treatment time | ||||||
>90 min | 73 (94) | 140 (92) | 1.25 (0.43–3.69) | 0.68 | 1.45 (0.39–5.46) | 0.58 |
≤90 min | 5 (6) | 12 (8) | 1.00 | |||
NIHSS score on admission | 1.22 (1.15–1.30)* | <0.0001* | 1.19 (1.11–1.28)* | <0.0001* | ||
>15 | 36 (46) | 11 (7) | - | - | ||
10–15 | 20 (26) | 32 (21) | - | - | ||
5–9 | 13 (17) | 61 (40) | - | - | ||
0–4 | 9 (11) | 48 (32) | - | - |
All variables included in the multivariate model are presented in the table. M1 = M1 segment of the middle cerebral artery. * per 1-point NIHSS score increase.
mRS: Modified Rankin scale. NIHSS: National Institute of Health Stroke Scale. DWI-ASPECTS: Diffusion-weighted imaging Alberta Stroke Programme Early CT score.