Table 1.
Clinical characteristics of NPC patients according to high and low CIP2A expression
|
Characteristics |
No. of patients |
Expression of CIP2A |
P
value |
|
|---|---|---|---|---|
| Low, n (%) | High, n (%) | |||
|
Age |
|
|
|
|
| ≤45 |
130 |
48 (50) |
82 (45) |
0.39 |
| >45 |
150 |
48 (50) |
102 (55) |
|
|
Sex |
|
|
|
|
| Male |
208 |
72 (75) |
136 (74) |
0.84 |
| Female |
72 |
24 (25) |
48 (26) |
|
|
WHO type |
|
|
|
|
| I + II |
10 |
2 (2) |
8 (6) |
0.50 |
| III |
270 |
94 (98) |
176 (94) |
|
|
VCA-IgA |
|
|
|
|
| < 1:80 |
41 |
16 (17) |
25 (14) |
0.49 |
| ≥ 1:80 |
239 |
80 (83) |
159 (86) |
|
|
EA-IgA |
|
|
|
|
| < 1:10 |
68 |
24 (25) |
44 (24) |
0.84 |
| ≥ 1:10 |
212 |
72 (75) |
140 (76) |
|
|
T Stage |
|
|
|
|
| T1-T2 |
137 |
55 (57) |
82 (45) |
0.04 |
| T3-T4 |
143 |
41 (43) |
102 (55) |
|
|
N Stage |
|
|
|
|
| N0-N1 |
173 |
61 (64) |
112 (61) |
0.66 |
| N2-N3 |
107 |
35 (36) |
72 (39) |
|
|
TNM Stage |
|
|
|
|
| I-II |
86 |
40 (42) |
46 (25) |
<0.01 |
| III-IV |
194 |
56 (58) |
138 (75) |
|
|
Locoregional failure |
|
|
|
|
| Yes |
38 |
11 (11) |
27 (15) |
0.46 |
| No |
242 |
85 (89) |
157 (85) |
|
|
Distant metastasis |
|
|
|
|
| Yes |
63 |
11 (11) |
52 (28) |
<0.01 |
| No |
217 |
85 (89) |
132 (72) |
|
|
Death |
|
|
|
|
| Yes |
67 |
14 (15) |
53 (29) |
0.01 |
| No | 213 | 82 (85) | 131 (71) | |