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. 2014 May 21;9(1):252. doi: 10.1186/1556-276X-9-252

Table 1.

Characterizations of nanoparticulate non-viral vectors in gene delivery

Non-viral vectors Transferring efficiency Preparation Cellular toxicity Applications References
Inorganic nanoparticles
Low
Easy
Frequently toxic
In vitro
[18,48,56]
Polymer-based nanoparticles
Low
Easy
Low toxicity
In vitro
[25,29,31]
Lipid-based nanoparticles
Low
Difficult
Toxic (at high dose)
In vitro
[20]
Hybrid nanoparticles High Easy Low toxicity In vitro/In vivo [25,73]