Table 1.
Non-viral vectors | Transferring efficiency | Preparation | Cellular toxicity | Applications | References |
---|---|---|---|---|---|
Inorganic nanoparticles |
Low |
Easy |
Frequently toxic |
In vitro |
[18,48,56] |
Polymer-based nanoparticles |
Low |
Easy |
Low toxicity |
In vitro |
[25,29,31] |
Lipid-based nanoparticles |
Low |
Difficult |
Toxic (at high dose) |
In vitro |
[20] |
Hybrid nanoparticles | High | Easy | Low toxicity | In vitro/In vivo | [25,73] |