Table 3.
Parameter | High dose OFS + P (N = 30) | Low dose OFS + P (N = 29) | Control (N = 29) |
---|---|---|---|
Baseline SLIM rating: Mean (SD) |
188.1 (33.9) |
164.9 (53.6) |
191.9 (44.0) |
SLIM rating at week 3: Mean (SD) |
200.4 (39.2) |
175.6 (50.1) |
185.9 (52.2) |
Mean change1 (SD) |
12.4 (37.7) |
10.8 (33.2) |
- 6.0 (31.1) |
LS Mean change2 |
13.8 (6.0) |
6.9 (6.2) |
- 3.7 (6.2) |
95% CI of LS mean change |
1.8, 25.8 |
- 5.5, 19.4 |
- 15.9, 8.6 |
Difference from control3 (SE) |
17.5 (8.6) |
10.6 (8.9) |
|
95% CI of difference from control | 0.5, 34.5 | −7.0, 28.3 |
1Mean Change was calculated as (Week 3 Mean–Baseline Mean).
2LS Mean Change adjusted for baseline Slim Scale AUC0-4hr effect, using analysis of covariance model.
3The difference from control is the difference in the LS Mean Changes of the active treatment minus the control. Overall treatment effect p-value = 0.1279.