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. 2014 Apr 17;14:36. doi: 10.1186/1472-6823-14-36

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Copyright © 2014 Ramkumar et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Histopathology. Gross photomicrograph showing a yellow colored well circumscribed tumour in the upper pole of the kidney (3a). Photomicrographs showing diffuse and trabecular arrangement of tumour cells (3b, 3c & 3d) with marked desmoplastic reaction at places (3e). (3b, 3c & 3d: H&E × 400 each, 3e: H&E × 200). Tumour cells are immunoreactive to chromogranin, synaptophysin and insulin (3f, 3g, 3h × 400 each). MIB 1 LI is 2% (d3i × 200). Electron micrographs showing numerous membrane bound electron dense neurosecretory granules, mitochondria and prominent rough endoplasmic reticulum (3j × 2550; 3k × 9000 original magnification).