Skip to main content
. 2014 Jun 5;4:5185. doi: 10.1038/srep05185

Figure 4. Knockdown of PTL-1 in touch neurons has a cell autonomous effect on neuronal ageing.

Figure 4

Strains labelled as zdIs5 or oxIs12 indicate the allele name of the gfp reporter, are wild-type at the SID-1 locus and do not contain a SID-1 transgene. SID-1 transgenic worms are labelled as “sid-1(qt2);TRN SID-1” to indicate the presence of the sid-1 mutation and Pmec-18::sid-1 transgene. The RNAi treatment is either empty vector (EV) or ptl-1 and is indicated after the strain name. (a) i. TRN imaging assay for animals carrying the zdIs5 reporter, indicating data for cell body branching, axon blebbing and axon branching. (a) ii. Micrograph shows an example of the axon branching phenotype. (b) GABAergic imaging assay for animals carrying the oxIs12 reporter. n for each sample is indicated in the table. Statistical analysis: chi-squared test, p-value is indicated by ns = not significant, *<0.05. Details of p-values are shown in Supplementary Table S1. Experiments were conducted twice independently, and the representative data shown are from one experiment.