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. 2014 May 31;13:133. doi: 10.1186/1476-4598-13-133

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Copyright © 2014 Zheng et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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A schematic presentation for the possible mechanisms of arsenic trioxide resistance in HCC and the synergistical anticancer mechanisms of arsenic trioxide/Nutlin-3 combination in the current study.