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Effect of CYP27A1 expression on fecal lipid content. Daily excretion of cholesterol, TGs, and bile acids was measured in feces collected from ApoE-KO, het, and DKO mice placed for 24 h in metabolic cages after 3 mo of CD (A) or WD (B). Results are presented as means ± sem (n=5). *P < 0.01, **P < 0.001, ***P < 0.0001.
