Table 3.

Predictors of Virologic Failure by Using Longitudinal Logistic Regression

		Univariate			Multivariate
Characteristic	N	OR	95%CI	p Value	aOR	95%CI	p Value
Male vs. female	207	6.46	(1.35–30.83)	0.02
Age (years)	207	0.9	(0.70–1.17)	0.44
Thai vs. Cambodia	207	3.09	(0.60–15.84)	0.18
Immediate-arm vs. deferred-arm	207	3.13	(0.91–10.76)	0.07
CDC classification B/C vs. N/A	207	1.88	(0.45–7.75)	0.38
NNRTI vs. PI based regimen	207	1.31	(0.17–10.35)	0.8
%CD4 at HAART initiation ≤20 % vs. >20%	207	0.49	(0.05–4.37)	0.52
%CD4 at baseline ≤20 % vs. >20%	207	1.11	(0.23–5.28)	0.9
HIV-RNA log10 copies at HAART initiation: ≥5 vs. <5 log10 copies/mL	207	3.39	(0.49–23.47)	0.22
Family status	196			0.36
Orphanage		Ref
Living with family; low or very low income		1.5	(0.21–10.80)
Living with family; ≥average income		0.35	(0.03–4.37)
Parent as primary caregiver (versus others)	199	0.38	(0.08–1.71)	0.21
Caregiver education: elementary/no education vs. high school/bachelor	198	5.69	(0.44–73.17)	0.18
Children not attending vs. attending school	199	1.25	(0.25–6.18)	0.79
Non HIV-disclosed vs. disclosed children	207	1.93	(0.34–10.89)	0.46
Tool 1. Percent adherence by pill count since the previous visit <95% vs. ≥95%	205	4.93	(2.09–11.63)	<0.001	4.56	(1.78–11.69)	0.002
Tool 2. PACTG questionnaire: Missed vs. never missed a dose in previous 3 days	204	3.66	(0.43–31.25)	0.236	3.22	(0.41–24.96)	0.264
Tool 2. Reported any barrier to adherence in the PACTG questionnaire	203	7.65	(2.75–21.26)	<0.001	7.08	(2.42–20.73)	<0.001
Tool 3. Child self-report missed dose vs. never missed a dose in previous 3 days	204	4.48	(0.92–21.81)	0.064	2.85	(0.52–15.76)	0.229
Tool 3. Child self-report missed dose vs. never missed a since the last clinic visit	207	6.18	(2.61–14.64)	<0.001	8.64	(1.96–38.04)	0.004