Table 3.

Effect of oxygen therapy on tubular necrosis, volume density of proximal convoluted tubules and tubular cast in gentamicin induced nephrotoxicity

Experimental groups	Tubular necrosis (score 0-4)	Volume density of PCT	Tubular cast (score 0-4)
1	0.24±0.05	0.229±0.009	0
2	1.91±0.29 *	0.093±0.011 *	1.83±0.30 *
3	1.38±0.24 *	0.120±0.015 *	1.66±0.21 *
4	1.06±0.19 *#	0.12±0.004 *#	0.83±0.30 *#
5	1.44±0.16 *	0.107±0.013 *	2.50±0.56 *
6	0.91±0.20 *#	0.16±0.015 *#	0.84±0.23 *#

Values represented as mean ±SEM. * Significant change in comparison with control At P< 0.05. # Significant change in comparison with gentamicin only treated at P< 0.05. group 1 as control; group 2 received daily GS (100 mg/kg Ip); group 3 received oxygen 2 hr daily for 2 days and then received daily GS; group 4 received oxygen 4 hr daily for 2 days and then received daily GS; group 5 received oxygen 4 hr daily for 4 days and then received daily GS and group 6 received oxygen 2 hr daily for 2 days and then during daily injection GS received 2 hr oxygen before injection