Table 4.

Effect of normobaric hyperoxia on renal malondialdehyde, glutathione and catalase in gentamicin induced nephrotoxicity

Experimental groups	Renal MDA (nmol/g protein)	Renal GSH (nmol/mg protein)	Renal CAT (u/mg protein)
Group 1	0.84 ± 0.202	0.681 ± 0.174	68.47 ± 14.58
Group 2	3.65 ± 0.581 *	0.293 ± 0.053 *	11.99 ± 4.4 *
Group 3	2.628 ± 0.465 *	0.274 ± 0.061 *	18.25 ± 3.41 *
Group 4	2.185 ± 0.596 *	0.203 ± 0.054 *	34.88 ± 8.49 * #
Group 5	2.905 ± 0.419 *	0.314 ± 0.084 *	26.85 ± 6.15 *
Group 6	1.921 ± 0.305 * #	0.261 ± 0.073 *	53.81 ± 8.26 #

Values represented as mean ±SEM. * Significant change in comparison with control At P < 0.05. # Significant change in comparison with gentamicin only treated at P < 0.05. group 1 as control; group 2 received daily GS (100 mg/kg Ip); group 3 received oxygen 2 hr daily for 2 days and then received daily GS; group 4 received oxygen 4 hr daily for 2 days and then received daily GS; group 5 received oxygen 4 hr daily for 4 days and then received daily GS and group 6 received oxygen 2 hr daily for 2 days and then during daily injection GS received 2 hr oxygen before injection