(A) Cumulative rate of aGVHD (Grade II–IV) incidence, analyzed according to the recipient rs4693608 SNP. The incidence was higher in possessors of the AA genotype compared with carriers of GG and AG genotypes (P=0.039). (B) Cumulative incidence of aGVHD (Grade II–IV), analyzed according to the discrepancy of rs4693608 SNP between recipient and donor. The D1 group consists of AA-GG and AA-AG recipient-donor pairs; the D2 group contains AA-AA, AG-AG, AG-GG, and AG-AA recipient-donor pairs; and the D3 group includes GG-GG, GG-AG, and GG-AA recipient-donor pairs. The incidence was higher in Group D1 compared with the D2 and D3 groups (P=0.0001).