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. Author manuscript; available in PMC: 2014 Jun 5.
Published in final edited form as: J Heart Lung Transplant. 2010 Apr 9;29(7):731–738. doi: 10.1016/j.healun.2010.02.007

Table 2.

Univariate associations of pre-transplant characteristics with 5-year survival

Recipient Characteristic Hazard Ratio P-value
 Age
  18 – 25 REF
  26 – 35 0.84 0.008
  36 – 45 0.81 0.001
  46 – 55 0.93 0.236
  56 – 65 1.12 0.031
  < 65 1.41 <0.001
 Female vs. Male 1.08 0.003
 Diagnosis
  COPD1 REF
  Idiopathic Pulmonary Fibrosis 1.30 <0.001
  Cystic Fibrosis 0.88 0.001
  Other Fibrosis2 1.23 <0.001
  Pulmonary Hypertension 1.29 <0.001
  Bronchiectasis 1.08 0.306
  Lymphangiomyomatosis 0.43 <0.001
  Other 1.07 0.409
 Body Mass Index 1.02 <0.001
 Creatinine 1.15 <0.001
 Total Bilirubin 1.02 <0.001
 Pulmonary Variables
  Oxygen Requirement, L/min 1.06 <0.001
  Carbon Dioxide, mEq/L 0.995 0.003
  FEV1 (L) 1.003 <0.001
  FVC (L) 1.000 0.711
  6 minute walk test < 150 feet 1.24 <0.001
  Mechanical ventilation 1.18 0.031
 Hemodynamic Variables
  Cardiac Output (L/min) 0.966 0.008
  Wedge Pressure (mm Hg) 0.998 0.468
  Systolic Pulmonary Artery Pressure 1.003 0.004
 Recipient Viral Status
  CMV positive status 1.017 0.584
  EBV positive status 0.86 0.003
  HCV positive status 1.24 0.039
 Co-morbidities
  Diabetes 1.13 0.002
  Hypertension 1.16 <0.001
  Cancer 1.10 0.232
  Transfusion History 1.30 <0.001
  Peptic Ulcer 1.18 0.011
  Cerebral Vascular 1.36 0.061
  Corticosteroid user 1.22 <0.001
1

COPD: Chronic Obstructive Pulmonary Disease and alpha-1 antitrypsin deficiency

2

Other fibrosis includes: rheumatoid arthritis, wegner’s granulomatosis-restrictive, pulmonary telengectasia, mixed connective tissue disease, polymyositis, silicosis, CREST, scleroderma, collagen vascular disease, connective tissue disease, desquamative interstitial pneumonitis, lymphocytic interstitial pneumonitis, restrictive lung disease, sjogren’s, occupational lung disease-other, pulmonary fibrosis(other specify).