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. 2014 May 31;7:325. doi: 10.1186/1756-0500-7-325

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Copyright © 2014 Grasic Kuhar and Matos; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Metastatic breast adenocarcinoma infiltrating liver. A. Hematoxylin & eosin staining. B. Immunohistochemistry human epidermal growth factor receptor 2 oncoprotein staining: 3+ (PathWay® Human Epidermal Growth Factor Receptor 2/neu 4B5; Roche Inc.). C. Amplification of the Human Epidermal Growth Factor Receptor 2/neu gene: score > 10 (PathVysion® human epidermal growth factor receptor 2 Probe Kit; Abbott Molecular Inc.).