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. 2012 Jan-Feb;5(1):52–60.

Table 2.

Estimated Overall Change of DACON 6 Months after Introduction of Reformulated Oxycodone CR from Interrupted Time Series Models

Medication strength Overall change (intercept + slope) 6 months after introduction P value
Daily tablets Change, %
Oxycodone CR
  All strengths −0.11 −3.7 <.001
  Highest strength 0.07 2.1 .003
  Lower strengths −0.09 −3.4 <.001
Oxymorphone ER
  All strengths 0.02 0.7 .611
  Highest strength 0.07 2.3 .236
  Lower strengths −0.03 −1.4 .087

CR indicates controlled release; DACON, daily average consumption; ER, extended release.