Table 2.

Dosing Ranges for Antiemetics Used for Primary Prophylaxis of CINV

Antiemetic	Dose	Antiemetic	Dose
NK1 receptor antagonists		Granisetron	2 mg oral or 1 mg oral twice daily; 1 mg IV or 0.01 mg/kg IV
Fosaprepitant	150 mg IV
Aprepitant	125 mg oral on day 1 and 80 mg oral on days 2 and 3	Dolasetron	100 mg oral
		Palonosetron	0.25 mg IV
5-HT3 receptor antagonists		Corticosteroid
Ondansetron	16–24 mg oral; 8 mg IV	Dexamethasone	8–20 mg oral IV

5-HT indicates serotonin; CINV, chemotherapy-induced nausea and vomiting; IV, intravenous; NK, neurokinin.