Figure 1.

Risks of major osteoporotic fracture and other rare events

Bis-AFF—bisphosphonate-associated atypical subtrochanteric and diaphyseal femur fracture, Bis-ONJ—bisphosphonate-associated osteonecrosis of the jaw, BMD—bone mineral density, FN—femoral neck, FRAX—Fracture Risk Assessment Tool, MVA—motor vehicle accident.

^*Data from Khan et al³³ (Canadian data).

^†Data from Dell et al³⁸ (American data).

^‡Data from Statistics Canada⁷⁷ (Canadian data).

^§Data from Transport Canada⁷⁸ (Canadian data).

^‖The 10-year risk of major osteoporotic fracture in a low-risk woman by Canadian FRAX (65-year-old woman, weighing 60 kg with a height of 168 cm; BMD FN T-score −1.2).

^¶The 10-year risk of major osteoporotic fracture in a moderate-risk woman by Canadian FRAX (65-year-old woman weighing 60 kg with a height of 168 cm; parent hip fracture history; BMD FN T-score −2.0).

^#The10-year risk of major osteoporotic fracture in a high-risk woman by Canadian FRAX (65-year-old woman weighing 60 kg with a height of 168 cm; parent hip fracture history; previous fracture; BMD FN T-score −2.6).