TABLE 2.
Comparison of BAL fluid and blood CMV viral loads with CMV IHC staining result
IHC staining result for CMVa | BAL fluid
|
Blood
|
||||
---|---|---|---|---|---|---|
CMV viral load (no. of copies/ml)
|
No. of samples | CMV viral load (no. of copies/ml)
|
No. of samples | |||
Median | Minimum-maximum | Median | Minimum-maximum | |||
Negative | 0 | 0-193,442 | 26 | 0 | 0-40,587 | 20 |
Atypical | 47,678 | 2,791-312,175 | 8 | 1,176 | 0-14,019 | 7 |
Typical | 1,548,827 | 555,505-2,450,702 | 5 | 189,013 | 0-1,491,020 | 5 |
P value | 0.001b | 0.010c | 0.028d | 0.15c |
Comparison of the differences in CMV viral loads between blood and BAL fluid were significantly different for the negative category (P = 0.21) and atypical category (P = 0.016), as stratified according to IHC characteristics (Wilcoxon signed-rank test). For the atypical category, load in BAL fluid was higher than that in blood.
Kruskal-Wallis test. For the negative samples, the CMV viral load in BAL samples was significantly different from those in both the atypical and typical samples (Dunn's multiple-comparison procedure).
Ordered logistic regression analysis.
Kruskal-Wallis test. The results for the negative and positive, typical samples were significantly different (Dunn's multiple-comparison procedure).