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. Author manuscript; available in PMC: 2015 May 2.
Published in final edited form as: Brain Res. 2014 Mar 15;1561:11–22. doi: 10.1016/j.brainres.2014.03.002

Fig. 3.

Fig. 3

Estradiol treatment enhances the up-regulation of the ER-α 14 days after SCI. Top panel: The ER-α is up-regulated in injured non-treated animals after 14 DPI when compared to sham group (p<0.005), according to Western blot studies. The up-regulation is more robust in injured animals treated with estradiol (E2) (p<0.005). Uterus (Ut) tissue was used as positive control as seen in lane 1. No changes were observed with GAPDH at each time point and all data was standardized accordingly (n=3). Bottom panel: Densitometric analysis represents the mean ± SEM and the statistical testing was performed at a pre-set alpha of p<0.05 (B). Comparison was made between sham/control and estradiol treated animals using ANOVA followed by Dunnet’s multiple comparisons post-hoc test (*p<0.005).