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. Author manuscript; available in PMC: 2015 May 2.
Published in final edited form as: Brain Res. 2014 Mar 15;1561:11–22. doi: 10.1016/j.brainres.2014.03.002

Fig. 7.

Fig. 7

Tamoxifen enhances functional recovery at late stages of SCI. A: BBB scores from TAM treated animals were not significantly different from control scores at 7 and 14 days post injury (DPI). However, TAM induced a significant change at 21 and 28 DPI (*p<0.05) according to Repeated Measures Two-way ANOVA followed by Bonferroni post hoc test. Results are mean ± SEM (Tamoxifen, n=10 and placebo, n=4). B–D: Determination of superoxide activity in spinal cord segments 28 days after injury in TAM-treated rats. Superoxides from rostral (B), epicenter (C), and caudal (D) segments of lesioned cord were determined by lucigenin chemiluminescence. The values shown are the mean ± SEM (n=4) and significance evaluated with an unpaired two-tailed student t-test (*p < .05 vs control).