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. 2014 Jan 24;15(Suppl 1):S11. doi: 10.1186/1471-2164-15-S1-S11

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© Wang et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Comparative organizations of penicillin biosynthetic genes cluster (PBC) in different strains. (A) PBC region of Wisconsin54-1255 is about 56.9-kb, consisting of 53.7-kb fragment and 3.2-kb shift fragment bounded by a conserved TGTAAA/T hexanucleotide. (B) PBC fragment arrangement schematic. We discovered a new shift fragment in NCPC10086, marked with orange bar and blue letters.