Table 4.
Rank correlations (ρ) and partial rank correlations (ρp) of the examined genomic properties with the divergence time of the paralogous adjacent genes.
| Genomic properties a | d S | T phy | ||
|---|---|---|---|---|
| ρ ( P -value) b | ρ p ( P -value) b,c | ρ ( P -value) b | ρ p ( P -value) b,c | |
| All adjacent paralogs | ||||
| d | 0.138 (<10-5) | 0.057 (0.056) | 0.141 (<10-6) | 0.053 (0.060) |
| #CTCF | 0.225 (<10-13) | 0.189 (<10-9) | 0.219 (<10-14) | 0.178 (<10-9) |
| ΔCpG O/E | 0.097 (<10-2) | 0.089 (<10-2) | 0.084 (<10-2) | 0.073 (<10-2) |
| Adjacent paralogs associated with GO terms in which high #CTCF/d genes were specifically enriched | ||||
| d | 0.086 (0.152) | -0.070 (0.245) | 0.108 (0.072) | -0.038 (0.526) |
| #CTCF | 0.292 (<10-6) | 0.276 (<10-5) | 0.273 (<10-5) | 0.243 (<10-4) |
| ΔCpG O/E | 0.122 (0.043) | 0.079 (0.186) | 0.132 (0.027) | 0.092 (0.125) |
a "d", intergenic distance; "#CTCF", number of overlapping CTCF-binding sites; "ΔCpG O/E", difference in upstream DNA methylation.
b P values show the probabilities of the observations under the hypothesis of no correlation.
c Spearman's partial correlation coefficient ρp is computed by controlling for the other two genomic properties listed in a