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. 2014 Jan 24;15(Suppl 1):S12. doi: 10.1186/1471-2164-15-S1-S12

Table 1.

Annotation result on high-coverage dataset A1

Methods Species-reference (~16.7 million reads) Order-reference (~20.0 million reads)
Accurate Higher Incorrect Unassigned Accurate Higher Incorrect Unassigned
MetaCluster-TA 60.9% 32.9% 4.0% 2.2% 31.8% 38.1% 22.6% 7.5%
MEGAN4 (contigs) 60.7% 12.9% 22.3% 4.1% 12.3% 13.1% 65.3% 9.3%
MEGAN4 (reads) 57.7% 14.8% 4.6% 22.8% 0.7% 0.7% 3.4% 95.2%

* "Accurate" corresponds to the percentage of species-reference/order-reference reads annotated correctly, i.e., their correct species/order names of the target genomes; "Higher" corresponds to the percentage of species-reference/order-reference reads that are correctly annotated, but to taxonomy of higher levels than species/order of the target genomes (e.g. reads of E. coli-reference annotated with family name Enterobacteriaceae); "Incorrect" corresponds to the percentage of reads which are annotated incorrectly; "Unassigned" corresponds to the percentage of reads that cannot be annotated to any taxonomy.

* Running time of MetaCluster-TA is about 8 hours; running time of MEGAN4 (reads) is about 4 days; running time of MEGAN4 (contigs) is about 1 day.

* About 80% reads can be aligned to contigs of length > 500 bp with <5% mismatches.