Table 2.
Median (interquartile range) concentrations of BNP-32 and NT-BNP-76 at baseline (first sample) and 5–6 months later (second sample) and median difference between the two by treatment group
| Variable | CKD 3–4 | Dialysis | Transplant |
|---|---|---|---|
| BNP-32 (pg/ml) | n=48 | n=102 | n=73 |
| First sample | 102 (48–252) | 218 (93–445) | 66 (41–148) |
| Second sample | 103 (34–269) | 280 (116–668) | 61 (31–161) |
| ΔBNP-32 | −9 (−47 to 39) | 13 (−66 to 171) | −4 (−20 to 19) |
| NT-BNP-76 (pg/ml) | n=49 | n=102 | n=71 |
| First sample | 698 (283 to 2,922) | 3850 (1776–12,323) | 379 (141–875) |
| Second sample | 2529 (347–9277)a | 18,830 (6114– 61,009)b | 347 (144–981) |
| ΔNT-BNP-76 | 778 (−57 to 7468) | 13,772 (2058–41,244) | 2 (−74 to 105) |
BNP-32, 32–amino acid BNP; BNP, B-type natriuretic peptide; ΔBNP, change between first and second samples.
a
P=0.004 compared with the first sample.
b
P<0.001 compared with the first sample.