Table 4.
Clinical characteristics of 42 PS-matched pairs of patients in the mPSL+PSL and PSL groups
Patient Characteristics | Initial Use of Corticosteroid | P Value | |
---|---|---|---|
mPSL+PSL | PSL | ||
Number | 42 | 42 | |
Baseline characteristics at initiation of corticosteroid | |||
Age, yr | 45 [28−62] | 41 [21−67] | 0.94 |
Men, n (%) | 27 (64.3) | 28 (66.7) | 0.83 |
Body mass index, kg/m2 | 22.9±2.8 | 23.0±3.1 | 0.91 |
Systolic BP, mmHg | 119±13 | 121±16 | 0.69 |
Diastolic BP, mmHg | 72±11 | 71±11 | 0.70 |
Use of antihypertensives, n (%) | 8 (19.0) | 8 (19.0) | 1.00 |
Creatinine, mg/dl | 0.9 [0.8−1.2] | 0.9 [0.7−1.3] | 0.96 |
Total cholesterol, mg/dl | 370±103 | 391±111 | 0.38 |
Albumin, g/dl | 1.9±0.5 | 1.9±0.6 | 0.91 |
Urinary protein, g/d | 7.4 [4.2−15.3] | 10.3 [4.0−15.6] | 0.86 |
Use of intravenous 25% albumin, n (%) | 22 (52.4) | 24 (57.1) | 0.56 |
Initial PSL dose, mg/kg | 0.75±0.13 | 0.69±0.15 | 0.08 |
First remission and relapse | |||
First remission, n (%) | 42 (100.0) | 41 (97.6) | |
Time to first remission, da | 12 [7−24] | 18 [12−25] | |
First relapse, n (%)a | 22 (52.4) | 31 (75.6) | |
Time to first relapse, yrb | 1.3 [0.8−1.7] | 0.8 [0.4−1.2] |
Values are given as mean±SD, median [interquartile range], or median (range). Conversion factors for units: serum creatinine in milligrams per deciliter to moles per liter, ×88.4; serum total cholesterol in milligrams per deciliter to moles per liter, ×0.02586.
Excluding one patient who was censored without remission after receiving immunosuppressive therapy.
Excluding 31 patients who were censored without relapse after receiving immunosuppressive therapy.